Cinnamic acids and derivatives
Medchemexpress LLC 3-Methylcinnamic acid | 3029-79-6 | 99.8% | C10H10O2 | 500 G
3-Methylcinnamic acid is a drug intermediate utilized for the synthesis of various active compounds. It is designated for research use only and is not sold to patients.
- Drug intermediate
- Utilized for the synthesis of various active compounds
- For research use only
- Not sold to patients
Apexbio Technology LLC Tyrphostin A1 2826-26-8 50mg
Tyrphostin A1 (CAS 2826-26-8) is a small molecule inhibitor targeting tyrosine kinase activity specifically involved in disrupting intracellular signaling pathways in immune cells It has been shown to interfere with CD40 ligand-induced signaling resulting in suppressed interleukin-12 (IL-12) secretion by macrophages and reduced differentiation of antigen-induced T helper 1 (Th1) cells Tyrphostin A1 is widely utilized in studies investigating cell-to-cell signaling immune response modulation and the mechanisms underlying inflammatory processes particularly in the context of autoimmune disease models
Medchemexpress LLC Ferulic acid 4-O-sulfate | 86321-29-1 | 98.1% | 274.25 | 5 MG
Ferulic acid 4-O-sulfate is a metabolite of Ferulic acid. It has been shown to relax arteries and lower blood pressure in mice. This compound causes significant concentration-dependent relaxations in mouse aorta, femoral, and saphenous arteries at concentrations of 0.1-30 μM.
- Metabolite of Ferulic acid
- Relaxes arteries
- Lowers blood pressure in mice
- Causes concentration-dependent relaxations in mouse aorta, femoral, and saphenous arteries
Medchemexpress LLC m-Coumaric acid (Standard) | 588-30-7 | 99.9% | 164.16 | 50 MG
m-Coumaric acid (Standard) is an analytical standard intended for research and analytical applications. It is a polyphenol metabolite from caffeic acid, formed by gut microflora, and is BBB-penetrant (blood-brain barrier) from chlorogenic acid.
- Stimulates cerebral nerves in vitro
- Evokes neurite outgrowth in hippocampal neuronal cells
- Promotes neuronal differentiation
- Increases spontaneous locomotor activity in mice
- Inhibits the oxidation of L-dopa by epidermis tyrosinase
- Attenuates non-catalytic protein glycosylation in retinas of diabetic rats
- Used as an analytical standard in HPLC, GC, and MS research experiments
Medchemexpress LLC Tyrphostin AG 528 | 133550-49-9 | MFCD01076474 | 98.0% | 306.32 | C18H14N2O3 | 10 MG
Tyrphostin AG 528 is a small-molecule protein tyrosine kinase inhibitor used as a research reagent for biochemical and cellular studies targeting EGFR and ErbB2. It is supplied as a solid with high purity and defined storage recommendations for long-term stability.
- Small-molecule inhibitor selective for EGFR and ErbB2.
- Reported IC50: EGFR 4.9 μM, ErbB2 2.1 μM.
- High purity (98.0%) suitable for preclinical research.
- Solid, light yellow to yellow appearance for easy handling.
- Molecular weight 306.32 and formula C18H14N2O3 for characterization.
- Available in small pack sizes for screening and assay development.
- Recommended storage: powder at -20°C (3 years) or 4°C (2 years).
Selleck Chemical LLC Tyrphostin AG 1296
Tyrphostin AG 1296 is an inhibitor of PDGFR with IC50 of 0 3-0 5 M no activity to EGFR Tyrphostin AG1296 inhibits FGFR and c-Kit with IC50 of 12 3 M and 1 8 M in Swiss 3T3 cells Tyrphostin AG1296 induces dramatic apoptosis in A375R cells
Cayman Chemical FerulIc AcId ethyl ester 10g
A lipophilic derivative of ferulic acid, with increased ability to cross cell membranes; less DPPH radical scavenging capacity than ferulic acid (IC50 = 66.7 μM for FAEE vs. 44.6 μM for ferulic acid); increases the expression of HO-1, Hsp70, and Hsp72, providing neuroprotection against amyloid β-peptide
Apexbio Technology LLC BIBF 1202 894783-71-2 10mg
BIBF 1202 (CAS 894783-71-2) is a carboxylate metabolite derivative of BIBF 1120 characterized as a selective inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2) kinase In biochemical assays BIBF 1202 demonstrates inhibitory activity against VEGFR2 kinase with an IC50 of 62 nM This compound is frequently employed in studies investigating the regulation of the VEGFR2 signaling pathway and its role in endothelial cell function Additionally BIBF 1202 is utilized in preclinical models related to tumor angiogenesis and associated pharmacological research
Waters Corp Ion Chamber, CI, MS System, Replacement Part
This replacement Ion Chamber is designed for Chemical Ionization (CI) applications within an MS System. It functions as a critical component, used specifically on the Xevo TQ-GC system.
- Categorized as a replacement parts kit
- Mechanical type
- Used in MS (Mass Spectrometry) systems
- Replaced as required
Cayman Chemical FerulIc AcId ethyl ester 1g
A lipophilic derivative of ferulic acid, with increased ability to cross cell membranes; less DPPH radical scavenging capacity than ferulic acid (IC50 = 66.7 μM for FAEE vs. 44.6 μM for ferulic acid); increases the expression of HO-1, Hsp70, and Hsp72, providing neuroprotection against amyloid β-peptide
eMolecules 2-Fluorocinnamic acid | 451-69-4 | MFCD00004370 | 25g
Matrix Scientific | 2-Fluorocinnamic acid | 25g | 389714243 | 4179 | 98.000 | 451-69-4 | MFCD00004370 | 166.151 | C9H7FO2
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eMolecules Building Block Tool
eMolecules 870779-01-4 | 2-(4'-Fluorobenzyloxy)phenylboronic acid | Combi-Blocks | MFCD07369749 | 246.040 | C13H12BFO3 | 98.000 | OB(O)c1ccccc1OCc1ccc(F)cc1 | 1g | 117525212
2-(4'-Fluorobenzyloxy)phenylboronic acid | Combi-Blocks | 870779-01-4 | MFCD07369749 | 246.040 | C13H12BFO3 | 98.000 | OB(O)c1ccccc1OCc1ccc(F)cc1 | 1g | 117525212
Selleck Chemical LLC AG 494
AG-494 a member of the tyrphostin family of tyrosine kinase inhibitors is a potent inhibitor of EGF receptor autophosphorylation (IC50 1 2 M) and EGF-dependent cell growth (IC50 6 M)